Technology
StratoSphereHL™ is a coated microsphere, with an inner core
consisting of the drug molecule and a minor amount of a matrix forming excipient,
and another excipient forming an outer coating which does not contain any drug.
Neither the excipients, nor the microsphere concept as such, are new to
the world of drug delivery. However, we've decided to let each excipient
do what it's best at, and to strictly keep them apart. The inner one
carries the drug, offering a mild and favourable environment both during
manufacturing, storage and use, as well as an exceptionally high
payload capacity. The outer one controls the release rate, through a
predictable degradation process trigged and maintained by the interstitial
aqueous environment in the s.c. or i.m. tissue into which the injection is made.
Sounds simple? We think so, with a combined 40+ years
in drug delivery and microspheres.
Let's put them to work for your drug molecule... (Contact)
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StratoSphereHL™ key features:
- Drug payload of up to 40-50%
- Radically reduced burst effect upon injection
- Encapsulation efficiency of >90%
- Maintained microenvironment pH
- Both excipients having prior use in marketed injectable drug products
- Patent protection until 2025
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